Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans
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منابع مشابه
Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans
The dynamic response of organisms exposed to environmental pathogens determines their survival or demise, and the outcome of this interaction depends on the host's susceptibility and pathogen-dependent virulence factors. The transmission of acquired information about the nature of a pathogen to progeny may ensure effective defensive strategies for the progeny's survival in adverse environments....
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Carbon dioxide is produced as a by-product of cellular respiration by all aerobic organisms and thus serves for many animals as an important indicator of food, mates, and predators. However, whether free-living terrestrial nematodes such as Caenorhabditis elegans respond to CO2 was unclear. We have demonstrated that adult C. elegans display an acute avoidance response upon exposure to CO2 that ...
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Chromatinmodifiers regulate lifespan in several organisms, raising the question of whether changes in chromatin states in the parental generation could be incompletely reprogrammed in the next generation and thereby affect the lifespan of descendants. The histone H3 lysine 4 trimethylation (H3K4me3) complex, composed of ASH-2,WDR-5 and the histone methyltransferase SET-2, regulates Caenorhabdit...
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Gene silencing is a significant obstacle to genome engineering and has been proposed to be a non-self response against foreign DNA. Yet, some foreign genes remain expressed for many generations and some native genes remain silenced for many generations. How organisms determine whether a sequence is expressed or silenced is unclear. Here we show that a stably expressed foreign DNA sequence in C....
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Life history events, such as traumatic stress, illness, or starvation, can influence us through molecular changes that are recorded in a pattern of characteristic chromatin modifications. These modifications are often associated with adaptive adjustments in gene expression that can persist throughout the lifetime of the organism, or even span multiple generations. Although these adaptations may...
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ژورنال
عنوان ژورنال: mBio
سال: 2017
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.01234-17